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Contrasting Roles for TLR Ligands in HIV-1 Pathogenes

· Citations to the Article (1) (Citation History) · Refereed Citations to the Article · Reads History · · Translate This Page Title: Contrasting Roles for TLR Ligands in HIV-1 Pathogenesis ...

Frontiers | TLR10 Senses HIV-1 Proteins and Significantly Enhances HIV-1 Infection | Immunolo

Immune activation is critical to HIV-1 infection and pathogenesis, leading to increased proinflammatory cytokine production, ... or 10 changes in response to various TLR ligands. MCF-10A, THP-1, and primary BM cells were stimulated with TLR ligands of ...

Christophe Vanpouille - Academia.e

Contrasting Roles for TLR Ligands in HIV-1 Pathogenesis more by Angélique Biancotto, Christophe Vanpouille, Melanie Merbah, and Jean-Charles Grivel Publication Date: 2010 ...

Contrasting roles for TLR ligands in HIV-1 pathogenesis. - CO

HIV-1, treatment with oligodeoxynucleotide (ODN) M362 (TLR9 agonist) suppressed both viral variants. The differential effects of these TLR ligands on HIV-1 replication correlated with changes in production of CC chemokines CCL3, CCL4 and ...

Expression of PD‐L1 and PD‐L2 on human macrophages is up‐regulated by HIV‐1 and differentially modulated by IL‐

HIV infection. PD-1 has two ligands: PD-L1, expressed on hematopoietic and nonhematopoietic cells, and PD-L2, limited to DCs and macrophages. Little is known about PD-L1 expression and regulation in human mac-rophages. ...

Dual role of autophagy in HIV-1 replication and pathogenesis | AIDS Research and Therapy | Full Te

Discussed is how autophagy plays dual roles in HIV-1 replication and HIV-1 disease progression. Autophagy, the major mechanism for degrading long-lived intracellular proteins and organelles, is essential for eukaryotic cell homeostasis. ...

Programmed necrosis in microbial pathogenes

[1–3] (Box 1). Necrosis has been traditionally regarded as accidental and uncontrolled cell death. How-ever, ... Toll-like receptor (TLR; see Glossary) ligands, or microbial Review Glossary Adapter proteins involved in signal transduction Apoptosis-associated ...

(PDF) Contrasting roles for TLR ligands in HIV-1 pathogenes

PDF | The first line of a host's response to various pathogens is triggered by their engagement of cellular pattern recognition receptors (PRRs). Binding of microbial ligands to these receptors leads to the induction of a variety of cellular factors that alter intracellular ...

Review Article Innate Immune Evasion Strategies by Human Immunodeficiency Virus Type

HIV-1 Induced Changes in Cytokine and Chemokine Profiles Cytokines and chemokines have the most in uential role in HIV- pathogenesis, and the virus exploits the network throughoutitslifecycle.HIV-infectionresultsintheactiva-tion of immune cells, altered in ...

The role of myeloid cell activation and arginine metabolism in the pathogenesis of virus-induced diseas

in the pathogenesis of virus-induced diseases Kristina S. Burrack andThomas E. Morrison* Department of Immunology and Microbiology, ...

Targeting of Toll-like receptors: a decade of progress in combating infectious diseas

emerging roles of TLR signalling in the pathogenesis of various infectious diseases and the therapeutic advantages ... Review, we discuss current knowledge on potential applications of TLR ligands as vaccine and drug candidates, which warrant further ...

Jundishapur Journal of Microbiology | Contemplating the Importance of Toll-like Receptors I and II Regarding Human Viral Pathogenes

Jundishapur Journal of Microbiology | Contemplating the Importance of Toll-like Receptors I and II Regarding Human Viral Pathogenesis

HIV-1 increases TLR responses in human primary astrocytes | Scientific Repor

production of IL-6 and IL-8 in response to TLR ligands was analyzed after HIV-1 infection with either X4 or R5 viruses. ... Viral-induced inflammation and dysregulation of cytokine expression play a major role in the pathogenesis of HIV-1 infection and 34,35 ...

Gene/environment interactions in the pathogenesis of autoimmunity: New insights on the role of Toll-like receptors - ScienceDire

Among endogenous TLR ligands involved in SSc onset there are cellular stress proteins, matrix-derived molecules, ... P.A. Silveira, S.T. GreyB cells in the spotlight: innocent bystanders or major players in the pathogenesis of type 1 diabetes Trends Endocrinol ...

Exposure to HIV-1 encoded TLR8 ligands enhances monocytes response to microbial encoded TLR2/4... - Europe PMC Article - Europe P

Background Chronic HIV-1 infection is characterized by high levels of persistent immune activation. Both HIV-1-encoded TLR7/8 ligands and TLR ligands encoded by products of microbial translocation have been implicated in inducing and sustaining immune ...

Toll Like Receptors Roles In Infection And Neuropathology | Download eBook PDF/EP

toll like receptors roles in infection and neuropathology Download toll like receptors roles in infection and neuropathology or read online here in PDF or EPUB. Please click button to get toll like receptors roles in infection and neuropathology book now. All books are ...

Jean-Charles Grivel | Hamad Bin Khalifa University - Academia.e

Contrasting Roles for TLR Ligands in HIV-1 Pathogenesis more by Angélique Biancotto, Christophe Vanpouille, Melanie Merbah, and Jean ...

Contrasting Roles for TLR Ligands in HIV-1 Pathogenes

These effects have been studied by applying TLR ligands to HIV-1-infected cell lines, isolated primary cells, human lymphocyte aggregate cultures and experimental animals –. However, critical events in HIV-1 pathogenesis occur in the context of structured ...

Publications Authored by Yana Kiselyeva | PubFac

Contrasting roles for TLR ligands in HIV-1 pathogenesis. Authors: Beda Brichacek Christophe Vanpouille Yana Kiselyeva Angelique Biancotto Melanie Merbah Ivan Hirsch Andrea Lisco Jean Charles Grivel Leonid Margolis ...

Contrasting roles for TLR ligands in HIV-1 pathogenesis | B. Brichacek | Request P

Request PDF on ResearchGate | On Jan 1, 2010, B. Brichacek and others published Contrasting roles for TLR ligands in HIV-1 pathogenesis We use cookies to make interactions with our website easy and meaningful, to better understand the use of our ...